Recombinant Human CD99L2 Protein (Fc Tag)

Specifications

Catalog number

PKSH032228-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD99 Antigen-Like Protein 2 (CD99L2) belongs to the CD99 family. CD99L2 is a single-pass type I membrane protein and expressed in many tissues; with low expression in thymus. CD99L2 plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.

Abbreviation

CD99L2

Synonyms

CD99; CD99 Antigen-Like Protein 2; CD99L2; MIC2-Like Protein 1; MIC2L1

UniProt

Q8TCZ2

Accession Number

Q8TCZ2

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Asp26-Ala188

Field of Research

Signal Transduction; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

44.5 kDa

Observed Molecular Weight

60-90 kDa

Species

Human