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Product details

Recombinant Human Cerberus/CER1 Protein (His Tag)

Catalog number PKSH032240-01

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Price for PKSH032240-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032240-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5) . DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in response to Nodal and Shh. Cerberus 1 binds BMP-4 and Nodal and inhibits their activities. The inhibitory functions of Cerberus favor mesodermal development in the anterior region of the gastrula and suppresses posterior mesodermal differentiation. In chick and Xenopus, Cerberus 1 also regulates, but is not required for embryonic left-right polarization, neurulation, and head and heart induction.
Abbreviation
Cerberus; CER1
Synonyms
CER1; Cerberus; Cerberus-Related Protein; DAN Domain Family Member 4; DAND4
UniProt
O95813
Accession Number
O95813
Expression System
HEK293 Cells
Tag
C-His
Sequence
Thr18-Ala267
Field of Research
Developmental Biology; immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
29.2 kDa
Observed Molecular Weight
35-42 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Cerberus/CER1 Protein (His Tag)?

The catalog number for Recombinant Human Cerberus/CER1 Protein (His Tag) is PKSH032240.

What sizes are available for Recombinant Human Cerberus/CER1 Protein (His Tag)?

Recombinant Human Cerberus/CER1 Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Cerberus/CER1 Protein (His Tag) come in?

Recombinant Human Cerberus/CER1 Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human Cerberus/CER1 Protein (His Tag) in stock?

Recombinant Human Cerberus/CER1 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Cerberus/CER1 Protein (His Tag)?

Recombinant Human Cerberus/CER1 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Cerberus/CER1 Protein (His Tag)?

Estimated delivery time for Recombinant Human Cerberus/CER1 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Cerberus/CER1 Protein (His Tag)?

The safety data sheet for Recombinant Human Cerberus/CER1 Protein (His Tag) is available here: https://789.bio/eb/z9KuLK.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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