Recombinant Human Collectin-11/COLEC11 Protein (His Tag)

Specifications

Catalog number

PKSH032268-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS) . It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2) .

Abbreviation

Collectin-11; COLEC11

Synonyms

CL-K1; COLEC11; Collectin Kidney Protein 1; Collectin-11

UniProt

Q9BWP8

Accession Number

Q9BWP8

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln26-Met271

Field of Research

Cell biology; Cardiovascular

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

27.1 kDa

Observed Molecular Weight

30-35 kDa

Species

Human