Recombinant Human CXADR/CAR Protein (His Tag)

Specifications

Catalog number

PKSH032284-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Coxsackievirus and Adenovirus Receptor (CAR) belongs to the CTX family of the Ig superfamily. CXADR is a type I transmembrane glycoprotein and expressed in pancreas, brain, heart, small intestine, testis, prostate. It is a receptor that mediates gene transfer and also act as an adhesion molecule within junctional complexes, notably between epithelial cells lining body cavities and within myocardial intercalated discs. CXADR contains an extracellular domain, a transmembrane helix and a C-terminal intracellular domain. The C-terminal interacts with few cytoplasmic junctional proteins, microtubules and the actin cytoskeleton.

Abbreviation

CXADR; CAR

Synonyms

CAR; CVB3-Binding Protein; CXADR; Coxsackievirus B-Adenovirus Receptor; Coxsackievirus and Adenovirus Receptor; HCVADR; hCAR

UniProt

P78310

Accession Number

P78310

Expression System

HEK293 Cells

Tag

C-His

Sequence

Leu20-Gly237

Field of Research

Signal Transduction; Microbiology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

25.1 kDa

Observed Molecular Weight

32 kDa

Species

Human