Recombinant Human CXCL1 Protein (His Tag)

Specifications

Catalog number

PKSH032290-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.

Abbreviation

CXCL1

Synonyms

C-X-C Motif Chemokine 1; CXCL1; GRO; GRO-Alpha (1-73) ; GRO1; GROA; Growth-Regulated Alpha Protein; MGSA; Melanoma Growth Stimulatory Activity; NAP-3; Neutrophil-Activating Protein 3; SCYB1

UniProt

P09341

Accession Number

P09341

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala35-Asn107

Field of Research

Immunology

Endotoxin

< 0.01 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

8.9 kDa

Observed Molecular Weight

10-14 kDa

Species

Human