Recombinant Human Cyclophilin E/PPIE Protein (His Tag)

Specifications

Catalog number

PKSH032317-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Peptidyl-prolyl cis-trans isomerase E, also known as Cyclophilin E, Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-type PPIase family of PPIase E subfamily. PPIE found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. PPIE contains one PPIase cyclophilin-type domain and one RRM (RNA recognition motif) domain. PPIE accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIE combines RNA-binding and PPIase activities. It may be involved in muscle- and brain-specific processes and pre-mRNA splici

Abbreviation

Cyclophilin E; PPIE

Synonyms

CYP33; Cyclophilin E; Cyclophilin-33; PPIE; PPIase E; Peptidyl-Prolyl Cis-Trans Isomerase E; Rotamase E

UniProt

Q9UNP9

Accession Number

Q9UNP9

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Val301

Field of Research

Signal Transduction; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

35.6 kDa

Observed Molecular Weight

34 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Species

Human