Recombinant Human Cyr61/CCN1 Protein (Fc Tag)

Specifications

Catalog number

PKSH032318-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10 , GIG1, CYR61, CCN1 and IGFBP10, belongs to the CCN family, CYR61 is a secreted protein and contains one CTCK (C-terminal cystine knot-like) domain, one IGFBP N-terminal domain, one TSP type-1 domain and one VWFC domain. CYR61 promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. CYR61 plays important roles in inflammation and tissue repair. CYR61 is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Abbreviation

Cyr61; CCN1

Synonyms

CCN family member 1; CCN1; CYR61; Cysteine-rich angiogenic inducer 61; GIG1; IGFBP10; Insulin-like growth factor-binding protein 10; Protein CYR61

UniProt

O00622

Accession Number

O00622

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Thr 25-Asp381

Field of Research

Signal Transduction; Cardiovascular; Cancer; immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

66.5 kDa

Observed Molecular Weight

71 kDa

Species

Human