Recombinant Human Cystatin C/CST3 Protein (Human Cells)

Specifications

Catalog number

PKSH032321-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B; H; K; L and S. As an inhibitor of cysteine proteinases; Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently; it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition) ; such as Alzheimer's disease.

Abbreviation

Cystatin C; CST3

Synonyms

CST3; Cystatin-3; Cystatin-C; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin

UniProt

P01034

Accession Number

P01034

Expression System

HEK293 Cells

Tag

None

Sequence

Ser27-Ala146

Field of Research

Tags & Cell Markers; Cell biology; Cardiovascular; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.3 kDa

Observed Molecular Weight

15 kDa

Species

Human