Recombinant Human Dermatopontin/DPT Protein (Fc & His Tag)

Specifications

Catalog number

PKSH032350-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.

Abbreviation

Dermatopontin; DPT

Synonyms

Dermatopontin; TRAMP and DPT; Tyrosine-rich acidic matrix protein

UniProt

Q07507

Accession Number

Q07507

Expression System

HEK293 Cells

Tag

C-Fc-His

Sequence

Gln19-Val201

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

49.9 kDa

Observed Molecular Weight

50-60 kDa

Species

Human