Recombinant Human dUTPase Protein

Specifications

Catalog number

PKSH032364-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial (dUTPase) belongs to the dUTPase family. dUTPase exits as a homotrimer and is involved in nucleotide metabolism. dUTPase produces dUMP; the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. The dUTPase increase in PCR product yield; length and fidelity enables further down-stream applications. These effects make dUTPase useful in PCR fidelity and yield-sensitive applications. dUTPase is specific for dUTP and is critical for the fidelity of DNA replication and repair.

Abbreviation

DUTPase

Synonyms

DUT; Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial; dUTP Pyrophosphatase; dUTPase

UniProt

P33316

Accession Number

P33316-2

Expression System

E.coli

Tag

None

Sequence

Met 1-Asn164

Field of Research

Epigenetics and Nuclear Signaling

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

17.7 kDa

Observed Molecular Weight

17 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Species

Human