• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Recombinant Human GFER Protein (His Tag)

Catalog number PKSH032412-01

Selecting a variant updates its price, size and availability.

Price for PKSH032412-01

Sign In for Pricing

Size / count 10 µg

Specifications

Catalog number
PKSH032412-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration. GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC) . S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines.
Abbreviation
GFER
Synonyms
ALR; Augmenter of liver regeneration; FAD-linked sulfhydryl oxidase ALR; GFER; HERV1; HPO; Hepatopoietin; hERV1
UniProt
P55789
Accession Number
P55789-2
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Asp125
Field of Research
Signal Transduction; Cell biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
17.3 kDa
Observed Molecular Weight
15 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human GFER Protein (His Tag)?

The catalog number for Recombinant Human GFER Protein (His Tag) is PKSH032412.

What sizes are available for Recombinant Human GFER Protein (His Tag)?

Recombinant Human GFER Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human GFER Protein (His Tag) come in?

Recombinant Human GFER Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human GFER Protein (His Tag) in stock?

Recombinant Human GFER Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human GFER Protein (His Tag)?

Recombinant Human GFER Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human GFER Protein (His Tag)?

Estimated delivery time for Recombinant Human GFER Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human GFER Protein (His Tag)?

The safety data sheet for Recombinant Human GFER Protein (His Tag) is available here: https://789.bio/eb/yfrvnP.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

You Might Also Like
CD7 (T3-3A1), CF405S conjugate, 0.1mg/mL
CD7 (T3-3A1), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040978-500
TGF-beta (1D11.16.8), CF647 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470977-100
Cytokeratin, LMW (AE-1), CF640R conjugate, 0.1mg/mL
Cytokeratin, LMW (AE-1), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400253-100
CD45RO (190-2F2.5), CF647 conjugate, 0.1mg/mL
CD45RO (190-2F2.5), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471081-100
HSP27 (G3.1), CF740 conjugate, 0.1mg/mL
HSP27 (G3.1), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740861-500
CD8 (C8/1035), CF568 conjugate, 0.1mg/mL
CD8 (C8/1035), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC681035-500
CD31 / PECAM-1 (158-2B3), CF640R conjugate, 0.1mg/mL
CD31 / PECAM-1 (158-2B3), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400352-100
TNF alpha (J2D10), CF640R conjugate, 0.1mg/mL
TNF alpha (J2D10), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400994-100