Recombinant Human FTH Protein

Specifications

Catalog number

PKSH032423-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ferritin heavy polypeptide 1 (FTH1) ; is a ubiquitous intracellular protein which stores iron in a soluble; non-toxic; readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein; including algae; bacteria; higher plants; and animals.

Abbreviation

FTH

Synonyms

Cell proliferation-inducing gene 15 protein; FHC; FTH; FTH1; FTHL6; Ferritin H subunit; Ferritin heavy chain; HFE5; PIG15

UniProt

P02794

Accession Number

P02794

Expression System

E.coli

Tag

None

Sequence

Met 1-Ser183

Field of Research

Signal Transduction; Cardiovascular; Neuroscience; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

21.2 kDa

Observed Molecular Weight

20 kDa

Species

Human