Recombinant Human FIBP Protein

Specifications

Catalog number

PKSH032428-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF) . It is postulated that FIBP may be involved in the mitogenic action of aFGF.

Abbreviation

FIBP

Synonyms

Acidic Fibroblast Growth Factor Intracellular-Binding Protein; FGF-1 Intracellular-Binding Protein; FIBP; aFGF Intracellular-Binding Protein

UniProt

O43427

Accession Number

NP_004205.2

Expression System

E.coli

Tag

None

Sequence

Met 1-Asp357

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

41.8 kDa

Observed Molecular Weight

40-50 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, pH8.0.

Species

Human