Recombinant Human FGF-17 Protein

Specifications

Catalog number

PKSH032434-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth; morphogenesis; tissue repair; tumor growth; and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signaling molecule in the induction and patterning of the embryonic brain. In addition; FGF17 stimulates the proliferation and activation of cells that express FGF receptors.

Abbreviation

FGF-17

Synonyms

FGF-17; FGF17; Fibroblast Growth Factor 17

UniProt

O60258

Accession Number

O60258

Expression System

E.coli

Tag

N-His

Sequence

Thr 23-Thr 216

Applications

Cell culture

Field of Research

Signal Transduction; Cardiovascular; Cancer

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50 2 x 105 IU/mg.5

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

23.3 kDa

Observed Molecular Weight

24 kDa

Species

Human