Recombinant Human FGF-7/KGF Protein

Specifications

Catalog number

PKSH032444-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities; and are involved in a variety of biological processes; including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor; whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.

Abbreviation

FGF-7; KGF

Synonyms

FGF-7; FGF7; Fibroblast growth factor 7; HBGF-7; Heparin-binding growth factor 7; KGF; Keratinocyte growth factor

UniProt

P21781

Accession Number

P21781

Expression System

E.coli

Tag

None

Sequence

Cys32-Thr194

Field of Research

Signal Transduction; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

18.9 kDa

Observed Molecular Weight

17 kDa

Species

Human