Recombinant Human FSH Protein (Flag & His Tag)

Specifications

Catalog number

PKSH032453-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH) . FSH and its familymembers are heterodimers consisting of non-covalently linked α- and β-subunits. They share an identical αsubunit, and β-subunits vary. FSH has a unique β-subunit (FSHβ), which confers its specific biologic activityand is responsible for interaction with the FSH-receptor which belongs to a subfamily of GPCRs calledleucine-rich-repeat-containing GPCRs (LGRs) . FSH is secreted from the pituitary gland and regulatesreproduction in mammals. FSH stimulates sertoli cell proliferation in testes and supports spermatogenesis inmales, and induces the maturation of ovarian follicles in females.

Abbreviation

FSH

Synonyms

FSH; FSH alpha/beta; Follicle-stimulating hormone

UniProt

P01215; P01225

Accession Number

P01215&P01225

Expression System

HEK293 Cells

Tag

C-Flag-His

Sequence

Ala25-Ser116&Asn19-Glu129

Field of Research

Signal Transduction; Neuroscience; Cancer; Developmental Biology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

11.5&13.5 kDa

Observed Molecular Weight

20-30 kDa

Species

Human