Recombinant Human Galectin 9/LGALS9 Protein (His Tag)

Specifications

Catalog number

PKSH032470-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.

Abbreviation

Galectin 9; LGALS9

Synonyms

Ecalectin; Gal-9; Galectin-9; LGALS9; Tumor Antigen HOM-HD-21

UniProt

Q3B8N1

Accession Number

Q3B8N1-2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Thr323

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

36.7 kDa

Observed Molecular Weight

49 kDa

Species

Human