Recombinant Human Galectin-3/LGALS3 Protein (His Tag)

Specifications

Catalog number

PKSH032473-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Galectin-3 (LGALS3) is also known as Galactose-specific lectin 3; Mac-2 antigen; Carbohydrate-binding protein 35; Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma; and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth; as a result providing a new mechanism for tumor immune tolerance.

Abbreviation

Galectin-3; LGALS3

Synonyms

35 kDa Lectin; CBP35; Carbohydrate-Binding Protein 35; GAL3; GALBP; GALIG; Gal-3; Galactose-Specific Lectin 3; Galactoside-Binding Protein; Galectin-3; IgE-Binding Protein; L-31; L31; LGALS2; LGALS3; Laminin-Binding Protein; Lectin L-29; MAC2; Mac-2 Antigen; P35

UniProt

P17931

Accession Number

AAH53667.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala2-Ile250

Field of Research

Cell biology; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

27.2 kDa

Observed Molecular Weight

35 kDa

Species

Human