Recombinant Human Galectin-7/LGALS7 Protein

Specifications

Catalog number

PKSH032475-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The Galectin family of proteins; with specificity for Nacetyllactosamine containing glycoproteins; consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs) .They also possess hemagglutination activity; which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. Although they are localized primarily in the cytoplasm and lack a classical signal peptide; they can be secreted by one or more as yet unidentified non-classical secretory pathways. They have diverse effects on many cellular functions including adhesion; migration; polarity; chemotaxis; proliferation; apoptosis; and differentiation. Galectins may play a key role in many pathological states; including autoimmune diseases; allergic reactions; inflammation; tumor cell metastasis; atherosclerosis; and diabetic complications.

Abbreviation

Galectin-7; LGALS7

Synonyms

Gal-7; Galectin-7; HKL-14; LGALS7; LGALS7B; PI7; PIG1; p53-Induced Gene 1 Protein

UniProt

P47929

Accession Number

P47929

Expression System

E.coli

Tag

None

Sequence

Met 1-Phe136

Field of Research

Neuroscience; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.07 kDa

Observed Molecular Weight

14 kDa

Species

Human