Recombinant Human TSTA3/SDR4E1 Protein (His Tag)

Specifications

Catalog number

PKSH032483-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

GDP-L-Fucose Synthase is a NADP (H) -binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.

Abbreviation

TSTA3; SDR4E1

Synonyms

5-Epimerase-4-Reductase; GDP-4-Keto-6-Deoxy-D-Mannose-3; GDP-L-Fucose Synthase; Protein FX; Red Cell NADP (H) -Binding Protein; SDR4E1; Short-Chain Dehydrogenase/Reductase Family 4E Member 1; TSTA3

UniProt

Q13630

Accession Number

Q13630

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Lys321

Field of Research

Signal Transduction; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

37.0 kDa

Observed Molecular Weight

40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Species

Human