Recombinant Human GGPS1 Protein (His Tag)

Specifications

Catalog number

PKSH032484-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Geranylgeranyl pyrophosphate synthase (GGPS1) is a member of the FPP/GGPP synthase family. GGPS1 is highly expressed in testis, heart and skeletal muscle. GGPS1 is localized in the cytoplasm and has geranylgeranyl diphosphate (GGPP) synthase activity. It catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Other transcriptional splice variants have been found.

Abbreviation

GGPS1

Synonyms

(2E,6E) -Farnesyl Diphosphate Synthase; Dimethylallyltranstransferase; Farnesyl Diphosphate Synthase; Farnesyltranstransferase; GGPP Synthase; GGPPSase; GGPS1; Geranylgeranyl Diphosphate Synthase; Geranylgeranyl Pyrophosphate Synthase; Geranyltranstransferase

UniProt

O95749

Accession Number

O95749

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Glu300

Field of Research

Cell biology; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

37.0 kDa

Observed Molecular Weight

35 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0.

Species

Human