Recombinant Human GMFB Protein (His Tag)

Specifications

Catalog number

PKSH032487-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Glia maturation factor beta (GMFB) contains a ADF-H domain, which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.

Abbreviation

GMFB

Synonyms

GMF; GMF-beta; Glia maturation factor beta

UniProt

P60983

Accession Number

P60983

Expression System

E.coli

Tag

C-His

Sequence

Met 1-His142

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

17.7 kDa

Observed Molecular Weight

18 kDa

Species

Human