Recombinant Human GFAP Protein (His Tag)

Specifications

Catalog number

PKSH032490-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.

Abbreviation

GFAP

Synonyms

GFAP; Glial Fibrillary Acidic Protein

UniProt

P14136

Accession Number

P14136

Expression System

E.coli

Tag

N-His

Sequence

Leu292-Met432

Field of Research

Signal Transduction; Tags & Cell Markers; Neuroscience; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

18.7 kDa

Observed Molecular Weight

17 kDa

Species

Human