Recombinant Human PLA2G16 Protein (His Tag)

Specifications

Catalog number

PKSH032509-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.

Abbreviation

PLA2G16

Synonyms

AdPLA; Adipose-Specific Phospholipase A2; Group XVI Phospholipase A1/A2; H-Rev 107 Protein Homolog; HRAS-Like Suppressor 1; HRAS-Like Suppressor 3; HRASLS3; HREV107; HREV107-1; HREV107-3; HRSL3; PLA2G16; Renal Carcinoma Antigen NY-REN-65

UniProt

P53816

Accession Number

P53816

Expression System

E.coli

Tag

N-His

Sequence

Asp12-Asp132

Field of Research

Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

14-17 kDa

Observed Molecular Weight

15 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM EDTA, pH8.0.

Species

Human