Recombinant Human HDGF Protein (His Tag)

Specifications

Catalog number

PKSH032539-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.

Abbreviation

HDGF

Synonyms

HDGF; HMG-1L2; HMG1L2; Hepatoma-Derived Growth Factor; High Mobility Group Protein 1-Kike 2

UniProt

P51858

Accession Number

P51858

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Tyr100

Field of Research

Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

12.6 kDa

Observed Molecular Weight

14 kDa

Species

Human