Recombinant Human IL18RAP/IL1R7 Protein (His Tag)

Specifications

Catalog number

PKSH032568-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

Abbreviation

IL18RAP; IL1R7

Synonyms

IL1R; ACPL; CD218b; CDw218b; IL-18RAcP; IL18RB; IL-18Rbeta; IL-18R-beta; IL-1R7; IL-1R-7; IL-1RAcPL; IL1R7; IL18RAP; IL-1RcPL; CDw218b; IL18Rβ Accessory protein like; Accessory protein-like; CD218 antigen-like family member B; I18RA; IL 18RAcP; IL 1R accessory protein like; IL 1R7; IL 1RAcPL; IL-18 receptor accessory protein; IL18Rbeta; IL-1R accessory protein-like; Interleukin 18 receptor accessory protein; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; Interleukin-18 receptor beta chain

UniProt

O95256

Accession Number

O95256

Expression System

HEK293 Cells

Tag

C-His

Sequence

Phe20-Arg356

Field of Research

Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

39.4 kDa

Observed Molecular Weight

56 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Species

Human