Recombinant Human IL-20RA/IL-20R1 Protein (Fc Tag)

Specifications

Catalog number

PKSH032575-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-20 Receptor Subunit α (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide; a 221 amino acid extracellular domain with two fibronectin type-III domains; a 24 amino acid transmembrane region; and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB; and the complex serves as a receptor for IL19; IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.

Abbreviation

IL-20RA; IL-20R1

Synonyms

UNQ; PRO; Cytokine Receptor Class-II Member; Cytokine Receptor Family 2 Member; CRF2; IL-20R; ZcytoR; CRF2-8; Cytokine Receptor Class-II Member 8; Cytokine Receptor Family 2 Member 8; IL-20 Receptor Subunit Alpha; IL-20R1; IL-20RA; IL-20R-Alpha; Interleukin-20 Receptor Subunit Alpha; ZcytoR7; IL20RA; UNQ681; PRO1315; alpha; class II cytokine receptor ZCYTOR7; CRF2 8; Cytokine receptor class II member 8; I20RA; IL 20R alpha; IL 20R1; Interleukin 20 receptor; Interleukin 20 receptor alpha chain; interleukin-20 receptor I

UniProt

Q9UHF4

Accession Number

Q9UHF4

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Val30-Lys250

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

52.4 kDa

Observed Molecular Weight

70-85 kDa

Species

Human