Recombinant Human Interleukin-13/IL-13 Protein (His Tag)

Specifications

Catalog number

PKSH032617-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

Abbreviation

Interleukin-13; IL-13

Synonyms

BHR; IL13; IL-13; P600; ALRH; BHR1; NC30; Interleukin-13

UniProt

P35225

Accession Number

AAH96139

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly35-Asn146

Applications

Cell culture

Field of Research

Cardiovascular; Cancer; immunology

Endotoxin

< 0.01 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.4 kDa

Observed Molecular Weight

13-30 kDa

Species

Human