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Product details

Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc)

Catalog number PKSH032633-01

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Price for PKSH032633-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032633-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin-22 (IL-22) is a member of a group of the IL-10 family; a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein; IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases; the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.
Abbreviation
IL-22
Synonyms
UNQ; IL-D; Interleukin; Cytokine Zcyto; TIFIL; zcyto; IL22; IL-21; IL-22; IL-D110; IL-TIF; ILTIF; TIFIL-23; TIFa; zcyto18; UNQ3099/PRO10096; UNQ3099; Interleukin-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; PRO10096; IL-D110; ILTIF; IL-TIF; TIFa; TIFIL-23; zcyto18
UniProt
Q9GZX6
Accession Number
Q9GZX6
Expression System
HEK293 Cells
Tag
C-hIgG4 Fc
Sequence
Ala34-Ile179
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
43.4 kDa
Observed Molecular Weight
50-75 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc)?

The catalog number for Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) is PKSH032633.

What sizes are available for Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc)?

Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) come in?

Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) is available in 2 different pack sizes.

Is Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) in stock?

Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc)?

Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc)?

Estimated delivery time for Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc)?

The safety data sheet for Recombinant Human Interleukin-22/IL-22 Protein (C-hIgG4 Fc) is available here: https://789.bio/eb/q9un9S.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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