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Product details

Recombinant Human Interleukin-4/IL-4 Protein (His Tag)

Catalog number PKSH032649-01

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Price for PKSH032649-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032649-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation; survival and gene expression. IL-4 is produced by mast cells; T cells; and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells; characterized by their cytokine-secretion profile that includes secretion of IL-4; IL-5; IL-6; IL-10; and IL-13; which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
Abbreviation
Interleukin-4; IL-4
Synonyms
Interleukin; B-cell growth factor; BSF; IL4; BCGF-1; BCGF1; BSF-1; BSF1; IL-4; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; Binetrakin; IGG1 induction factor; Interleukin-4; Lymphocyte stimulatory factor 1; Pitrakinra; IL2
UniProt
P05112
Accession Number
P05112
Expression System
HEK293 Cells
Tag
C-His
Sequence
His25-Ser153
Applications
Cell culture
Field of Research
Cancer; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.05-0.5 ng/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
16.0 kDa
Observed Molecular Weight
17-22&15 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Interleukin-4/IL-4 Protein (His Tag)?

The catalog number for Recombinant Human Interleukin-4/IL-4 Protein (His Tag) is PKSH032649.

What sizes are available for Recombinant Human Interleukin-4/IL-4 Protein (His Tag)?

Recombinant Human Interleukin-4/IL-4 Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Interleukin-4/IL-4 Protein (His Tag) come in?

Recombinant Human Interleukin-4/IL-4 Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human Interleukin-4/IL-4 Protein (His Tag) in stock?

Recombinant Human Interleukin-4/IL-4 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Interleukin-4/IL-4 Protein (His Tag)?

Recombinant Human Interleukin-4/IL-4 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Interleukin-4/IL-4 Protein (His Tag)?

Estimated delivery time for Recombinant Human Interleukin-4/IL-4 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Interleukin-4/IL-4 Protein (His Tag)?

The safety data sheet for Recombinant Human Interleukin-4/IL-4 Protein (His Tag) is available here: https://789.bio/eb/K0qLG4.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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