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Product details

Recombinant Human Interleukin-7/IL-7 Protein (His Tag)

Catalog number PKSH032654-01

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Price for PKSH032654-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032654-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT; which regulate lymphocyte survival; glucose uptake; proliferation; and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
Abbreviation
Interleukin-7; IL-7
Synonyms
Lymphopoietin; IL7; IL-7; IL 7; Interleukin 7; Interleukin-7; LP-1; Lymphopoietin 1
UniProt
P13232
Accession Number
P13232
Expression System
HEK293 Cells
Tag
C-His
Sequence
Asp26-His177
Applications
Cell culture
Field of Research
Immunology
Endotoxin
< 0.01 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL) . The ED50 for this effect is 50-300 pg/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
18.4 kDa
Observed Molecular Weight
19-30 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Interleukin-7/IL-7 Protein (His Tag)?

The catalog number for Recombinant Human Interleukin-7/IL-7 Protein (His Tag) is PKSH032654.

What sizes are available for Recombinant Human Interleukin-7/IL-7 Protein (His Tag)?

Recombinant Human Interleukin-7/IL-7 Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Interleukin-7/IL-7 Protein (His Tag) come in?

Recombinant Human Interleukin-7/IL-7 Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human Interleukin-7/IL-7 Protein (His Tag) in stock?

Recombinant Human Interleukin-7/IL-7 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Interleukin-7/IL-7 Protein (His Tag)?

Recombinant Human Interleukin-7/IL-7 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Interleukin-7/IL-7 Protein (His Tag)?

Estimated delivery time for Recombinant Human Interleukin-7/IL-7 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Interleukin-7/IL-7 Protein (His Tag)?

The safety data sheet for Recombinant Human Interleukin-7/IL-7 Protein (His Tag) is available here: https://789.bio/eb/Tq5Wr1.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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