Recombinant Human IL-8/CXCL8 Protein

Specifications

Catalog number

PKSH032656-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types; including T cells; endothelial cells and fibroblasts; in response to an inflammatory stimulus and acts by recruiting neutrophils; T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.

Abbreviation

IL-8; CXCL8

Synonyms

CXCL; Interleukin; C-X-C motif chemokine; Chemokine (C-X-C motif) ligand; IL8/CXCL; GCP; NAP; CXCL8; GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1;3-10C; AMCF-I; IL8/CXCL8; K60; Interleukin-8; IL-8; Emoctakin; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Granulocyte chemotactic protein 1 (GCP-1) ; Monocyte-derived neutrophil chemotactic factor (MDNCF) ; (Ala-IL-8) 77; (Ser-IL-8) 72;9E3; Beta thromboglobulin like protein; CEF-4; chemokine; CXC motif; GCP/IL-8 protein I; GCP/IL-8 protein II; GCP/IL-8 protein III; GCP/IL-8 protein IV; GCP/IL-8 protein V; GCP/IL-8 protein VI; Granulocyte chemotactic protein 1; IL-8 (1-77) ; IL-8 (9-77) ; IL8/NAP1 form I; IL8/NAP1 form II; IL8/NAP1 form III; IL8/NAP1 form IV; IL8/NAP1 form V; IL8/NAP1 form VI; Inteleukin 8; ligand 8; Lymphocyte-derived neutrophil-activating factor; MDNCF-b; MDNCF-c; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil activating peptide 1; Neutrophil activating protein 1; Neutrophil-activating factor; Neutrophil-activating protein 1; Protein 3 10C; Protein 3-10C; SCYB8; Small inducible cytokine subfamily B member 8; T cell chemotactic factor; T-cell chemotactic factor; TSG1

UniProt

P10145

Accession Number

P10145

Expression System

E.coli

Tag

C-His

Sequence

Ser28-Ser99

Applications

Cell culture

Field of Research

Cardiovascular; Cancer; immunology

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

9.3 kDa

Observed Molecular Weight

11 kDa

Species

Human