Recombinant Human Kallikrein 10/KLK10 Protein (His Tag)

Specifications

Catalog number

PKSH032665-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Abbreviation

Kallikrein 10; KLK10

Synonyms

KLK10; Kallikrein-10; NES1; Normal Epithelial Cell-Specific 1; PRSSL1; Protease Serine-Like 1

UniProt

O43240

Accession Number

AAH02710.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala31-Asn276

Field of Research

Signal Transduction; Cell biology; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

28.0 kDa

Observed Molecular Weight

34 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Species

Human