Recombinant Human Kallikrein 4/KLK4 Protein (His Tag)

Specifications

Catalog number

PKSH032667-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Abbreviation

Kallikrein 4; KLK4

Synonyms

AI2A1; ARM1; EMSP; EMSP1; Enamel Matrix Serine Proteinase 1; KLK-L1; KLK4; Kallikrein-4; Kallikrein-Like Protein 1; PRSS17; PSTS; Prostase; Serine Protease 17; kallikrein

UniProt

Q9Y5K2

Accession Number

Q9Y5K2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ser27-Ser254 (His197Gln)

Field of Research

Signal Transduction; Cell biology; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

25.4 kDa

Observed Molecular Weight

25-32 kDa

Species

Human