Recombinant Human Kallikrein 5/KLK5 Protein (His Tag)

Specifications

Catalog number

PKSH032668-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Abbreviation

Kallikrein 5; KLK5

Synonyms

KLK-L2; KLK5; Kallikrein-5; Kallikrein-Like Protein 2; SCTE; Stratum Corneum Tryptic Enzyme

UniProt

Q9Y337

Accession Number

Q9Y337

Expression System

HEK293 Cells

Tag

C-His

Sequence

Val23-Ser293

Field of Research

Signal Transduction; Cell biology; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

30.7 kDa

Observed Molecular Weight

40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 10% Glycerol, pH 5.5.

Species

Human