Recombinant Human Arginase-2/ARG2 Protein (His Tag)

Specifications

Catalog number

PKSH032673-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase.

Abbreviation

Arginase-2; ARG2

Synonyms

ARG2 ; Arginase-2; Kidney-type arginase; Non-hepatic arginase; Type II arginase; mitochondrial

UniProt

P78540

Accession Number

P78540

Expression System

E.coli

Tag

C-His

Sequence

His24-Gly330

Field of Research

Signal Transduction; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

34.2 kDa

Observed Molecular Weight

33 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH 7.5.

Species

Human