Recombinant Human Lactotransferrin/LTF Protein (His Tag)

Specifications

Catalog number

PKSH032679-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; and Lactoferroxin-C. Lactoferroxin A; Lactoferroxin B; and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors; while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide; fungicide) and is part of the innate defense; mainly at mucoses.

Abbreviation

Lactotransferrin; LTF

Synonyms

GIG12; HEL110; HLF2; Kaliocin-1; LF; LTF; Lactoferrin; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C; Lactotransferrin; Talalactoferrin

UniProt

P02788

Accession Number

AAH15822.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly20-Lys711

Field of Research

Cardiovascular; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

77.3 kDa

Observed Molecular Weight

90 kDa

Species

Human