Recombinant Human LRRN2 Protein (His Tag)

Specifications

Catalog number

PKSH032690-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) is a single-pass type I membrane protein that belongs to the LRRTM family. It contains ten LRR (leucine-rich) repeats, one LRRCT domain, and one LRRNT domain. LRRTM2 is expressed in neuronal tissues, and it interacts with DLG4 and NRXN1. LRRTM2 has been suggested to be involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. LRRTM2 also regulates the surface expression of AMPA receptors. LRRTM2 acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.

Abbreviation

LRRN2

Synonyms

KIAA0416; LRRN2; LRRTM2; Leucine-Rich Repeat Neuronal 2 Protein; Leucine-Rich Repeat Transmembrane Neuronal Protein 2

UniProt

O43300

Accession Number

O43300

Expression System

HEK293 Cells

Tag

C-His

Sequence

Cys34-Arg422

Field of Research

Neuroscience; Developmental Biology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

45.6 kDa

Observed Molecular Weight

74 kDa

Species

Human