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Product details

Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)

Catalog number PKSH032695-01

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Price for PKSH032695-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032695-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
SERPINB1 is a member of the serpin family and Ov-serpin subfamily. As protease inhibitors; serpins have an array of functions including regulating blood coagulation; fibrinolysis; the complement pathway; angiogenesis; inflammation; tumor suppression; extracellular matrix remodeling; and cell motility. SERPINB1 regulates the activity of the neutrophil proteases elastase; cathepsin G; proteinase-3; chymase; chymotrypsin; and kallikrein-3. Reactive bond 1 of SerpinB1 is specific for reaction with chymotrypsin-like protease such as cathepsin G; chymotrypsin or chymase. Reactive bond 2 of SerpinB1 is specific for reaction with elastase-like protease such as neutrophyl elastase; proteinase-3; pancreatic elastase or PSA. In addition; SERPINB1 also functions as a potent intracellular inhibitor of granzyme H.
Abbreviation
SERPINB1; PI2
Synonyms
EI; ELANH2; HEL-S-27; HEL57; LEI; Leukocyte elastase inhibitor; M/NEI; MNEI; Monocyte/neutrophil elastase inhibitor; PI-2; PI2; Peptidase inhibitor 2; SERPINB1
UniProt
P30740
Accession Number
P30740
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Pro379
Field of Research
Cell biology; Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
43.8 kDa
Observed Molecular Weight
40-56 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)?

The catalog number for Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) is PKSH032695.

What sizes are available for Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)?

Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) come in?

Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) is available in 2 different pack sizes.

Is Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) in stock?

Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)?

Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)?

Estimated delivery time for Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)?

The safety data sheet for Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag) is available here: https://789.bio/eb/rvTCaL.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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