Recombinant Human LTA4H Protein (His Tag)

Specifications

Catalog number

PKSH032704-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity

Abbreviation

LTA4H

Synonyms

LTA-4 hydrolase; LTA4; LTA4H; Leukotriene A (4) hydrolase; Leukotriene A-4 hydrolase

UniProt

P09960

Accession Number

P09960

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Asp611

Field of Research

Cancer; immunology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

70.3 kDa

Observed Molecular Weight

60-70 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM MES, 2mM EDTA, 20% Glycerol, pH 5.0.

Species

Human