Recombinant Human LRP12 Protein (His Tag)

Specifications

Catalog number

PKSH032710-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.

Abbreviation

LRP12

Synonyms

LRP-12; LRP12; Low-Density Lipoprotein Receptor-Related Protein 12; ST7; Suppressor of Tumorigenicity 7 Protein

UniProt

Q9Y561

Accession Number

Q9Y561

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asn28-Ile488

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

52.5 kDa

Observed Molecular Weight

68 kDa

Species

Human