Recombinant Human DCXR Protein (His Tag)

Specifications

Catalog number

PKSH032714-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into Xylitol. L-Xylulose Reductase catalyzes the NADPH-dependent reduction of several Pentoses, Tetroses, Trioses, α-Dicarbonyl compounds and L-Xylulose. L-Xylulose Reductase participates in the Uronate Cycle of Glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing Xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

Abbreviation

DCXR

Synonyms

Carbonyl Reductase II; DCXR; Dicarbonyl/L-Xylulose Reductase; Kidney Dicarbonyl Reductase; L-Xylulose Reductase; Sperm Surface Protein P34H; XR; kiDCR

UniProt

Q7Z4W1

Accession Number

Q7Z4W1

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Cys244

Field of Research

Signal Transduction; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

28.1 kDa

Observed Molecular Weight

29 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 1mM DTT, 30% Glycerol, 1mM DTT, pH 8.0.

Species

Human