Recombinant Human LTBR/TNFRSF3 Protein (Fc Tag)

Specifications

Catalog number

PKSH032718-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Tumor necrosis factor receptor superfamily member 3; also known as Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; LTBR; TNFCR; TNFR3 and TNFRSF3; is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types; but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition; LTBR can lead to the release of the cytokine interleukin 8.

Abbreviation

LTBR; TNFRSF3

Synonyms

D12S370; LTBR; Lymphotoxin-Beta Receptor; TNF-RIII; TNFCR; TNFR-III; TNFR3; TNFRSF3; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor 2-Related Protein; Tumor Necrosis Factor Receptor Superfamily Member 3; Tumor Necrosis Factor Receptor Type III

UniProt

P36941

Accession Number

P36941

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gln31-Met227

Field of Research

Signal Transduction; Cell biology; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

48.8 kDa

Observed Molecular Weight

61 kDa

Species

Human