Recombinant Human MAA/GSTZ1 Protein (His Tag)

Specifications

Catalog number

PKSH032732-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.

Abbreviation

MAA; GSTZ1

Synonyms

GSTZ1; GSTZ1-1; Glutathione S-Transferase Zeta 1; MAAI; Maleylacetoacetate Isomerase

UniProt

O43708

Accession Number

O43708

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Ala216

Field of Research

Signal Transduction; Tags & Cell Markers; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

25.2 kDa

Observed Molecular Weight

25-30 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 1mM DTT, pH 8.0.

Species

Human