Recombinant Human MGAT2/GlcNAc-TII Protein (His Tag)

Specifications

Catalog number

PKSH032737-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.

Abbreviation

MGAT2; GlcNAc-TII

Synonyms

2-N-acetylglucosaminyltransferase II;6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Alpha-1; Beta-1; GlcNAc-T II; MGAT2; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; NT-II

UniProt

Q10469

Accession Number

Q10469

Expression System

HEK293 Cells

Tag

C-His

Sequence

Arg30-Gln447

Field of Research

Tags & Cell Markers

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

49.3 kDa

Observed Molecular Weight

50 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Species

Human