Recombinant Human M-CSF/CSF1 Protein (His Tag)

Specifications

Catalog number

PKSH032741-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.

Abbreviation

M-CSF; CSF1

Synonyms

CSF-1; CSF1; Lanimostim; M-CSF; MCSF; Macrophage Colony-Stimulating Factor 1; SCF-1

UniProt

P09603

Accession Number

P09603

Expression System

HEK293 Cells

Tag

C-His

Sequence

Glu33-Arg255

Applications

Cell culture

Field of Research

Cardiovascular; immunology

Endotoxin

< 0.01 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

26.2 kDa

Observed Molecular Weight

41 kDa

Species

Human