Recombinant Human LAMTOR3/MP1 Protein (His Tag)

Specifications

Catalog number

PKSH032742-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.

Abbreviation

LAMTOR3; MP1

Synonyms

LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MAP2K1IP; MEK-Binding Partner 1; Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1; Mitogen-Activated Protein Kinase Scaffold Protein 1; Mp1; Ragulator Complex Protein LAMTOR3

UniProt

Q9UHA4

Accession Number

Q9UHA4

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Val124

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

15.8 kDa

Observed Molecular Weight

15 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 5mM DTT, 30% Glycerol, pH 8.0.

Species

Human