Recombinant Human MAP1D Protein (His Tag)

Specifications

Catalog number

PKSH032749-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.

Abbreviation

MAP1D

Synonyms

MAP 1D; MAP1D; METAP1D; MetAP 1D; Metap1l; Methionine Aminopeptidase 1D Mitochondrial; Methionyl Aminopeptidase Type 1D Mitochondrial

UniProt

Q6UB28

Accession Number

Q6UB28

Expression System

E.coli

Tag

N-His & C-His

Sequence

Arg44-Ala335

Field of Research

Signal Transduction; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

35.4 kDa

Observed Molecular Weight

35-40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Species

Human