Recombinant Human MECP2 Protein (His Tag)

Specifications

Catalog number

PKSH032751-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may also be necessary for the function of other types of brain cells.

Abbreviation

MECP2

Synonyms

MECP2; MeCp-2 protein; Methyl-CpG-binding protein 2

UniProt

P51608

Accession Number

P51608

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Ser486

Field of Research

Neuroscience; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

53.5 kDa

Observed Molecular Weight

90 kDa

Species

Human