Recombinant Human MAP1LC3A Protein (His Tag)

Specifications

Catalog number

PKSH032755-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) belongs to the MAP1 LC3 family. MAP1LC3A is found most abundantly in the heart, brain, liver, skeletal muscle, and testis. But it is absent in the thymus and peripheral blood leukocytes. MAP1LC3A is thought to take part in the formation of autophagosomal vacuoles and is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. In addition, MAP1A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity.

Abbreviation

MAP1LC3A

Synonyms

Autophagy-Related Protein LC3 A; Autophagy-Related Ubiquitin-Like Modifier LC3 A; MAP1 Light Chain 3-Like Protein 1; MAP1A/MAP1B LC3 A; MAP1A/MAP1B Light Chain 3 A; Microtubule-Associated Protein 1 Light Cha; Microtubule-Associated Proteins 1A/1B Light Chain 3A

UniProt

Q9H492

Accession Number

Q9H492

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Phe121

Field of Research

Signal Transduction; Cardiovascular; Neuroscience; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

15.3 kDa

Observed Molecular Weight

18 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 100mM NaCl, pH 8.0.

Species

Human